| 20451 | Steve Coogan | 19,876 | 6 | 381 |
| 20452 | Steve Davis | 19,205 | 6 | 313 |
| 20453 | Steven Kwan | 16,030 | 6 | 454 |
| 20454 | Stewart Resnick | 52,891 | 6 | 65 |
| 20455 | Stormi Henley | 25,126 | 6 | 214 |
| 20456 | Strom Thurmond | 187,994 | 6 | 12 |
| 20457 | Stéphane Séjourné | 122,776 | 6 | 31 |
| 20458 | Suez Canal | 22,732 | 6 | 308 |
| 20459 | Sukhdev Singh Gogamedi | 49,190 | 6 | 71 |
| 20460 | Sukhoi Su-27 | 40,889 | 6 | 110 |
| 20461 | Sukhoi Su-30MKI | 22,490 | 6 | 263 |
| 20462 | Sukihana | 45,545 | 6 | 68 |
| 20463 | Suleiman Obeid | 76,162 | 6 | 22 |
| 20464 | SummerSlam | 25,776 | 6 | 221 |
| 20465 | Sunil (actor) | 16,277 | 6 | 424 |
| 20466 | Sunita Lyn Williams | 21,451 | 6 | 264 |
| 20467 | Sunny Sanskari Ki Tulsi Kumari | 14,591 | 6 | 386 |
| 20468 | Super Bowl LVI halftime show | 68,230 | 6 | 83 |
| 20469 | Super Bowl LVII halftime show | 57,676 | 6 | 104 |
| 20470 | Super Bowl XLV | 28,711 | 6 | 278 |
| 20471 | Super Bowl XXV | 25,631 | 6 | 305 |
| 20472 | Super Bowl XXVII | 29,880 | 6 | 203 |
| 20473 | Super Bowl XXXVII | 19,878 | 6 | 378 |
| 20474 | Superman II | 10,111 | 6 | 775 |
| 20475 | Survivor Series (2023) | 29,927 | 6 | 174 |
| 20476 | Susan Downey | 158,996 | 6 | 35 |
| 20477 | Swapna Dutt | 16,379 | 6 | 502 |
| 20478 | Swimming at the Summer Olympics | 13,728 | 6 | 713 |
| 20479 | Swiped (2025 film) | 26,171 | 6 | 205 |
| 20480 | Sycamore Gap Tree | 182,686 | 6 | 13 |
| 20481 | Sycamore Gap tree | 50,248 | 6 | 74 |
| 20482 | Sylvester Turner | 136,797 | 6 | 23 |
| 20483 | Séamus Coleman | 20,138 | 6 | 314 |
| 20484 | T-90 | 26,037 | 6 | 220 |
| 20485 | T. D. Jakes | 30,458 | 6 | 176 |
| 20486 | Taeil (singer) | 40,607 | 6 | 56 |
| 20487 | Taekwondo at the 2024 Summer Olympics | 45,910 | 6 | 126 |
| 20488 | Tahnee Welch | 326,411 | 6 | 5 |
| 20489 | Taiwo Awoniyi | 21,342 | 6 | 271 |
| 20490 | Taj: Divided by Blood | 24,034 | 6 | 186 |
| 20491 | Takahiro Shiraishi | 195,775 | 6 | 10 |
| 20492 | Tame Impala | 18,685 | 6 | 328 |
| 20493 | Tamera Mowry | 25,538 | 6 | 181 |
| 20494 | Tamim Iqbal | 32,049 | 6 | 137 |
| 20495 | Tan France | 18,277 | 6 | 468 |
| 20496 | Tanhaji | 28,933 | 6 | 154 |
| 20497 | Tara Sutaria | 19,994 | 6 | 376 |
| 20498 | Target Corporation | 28,675 | 6 | 175 |
| 20499 | Tati Westbrook | 25,836 | 6 | 220 |
| 20500 | Tatiana Suarez | 89,776 | 6 | 36 |