| 20401 | Skype | 33,733 | 6 | 108 |
| 20402 | Slammiversary | 128,761 | 6 | 14 |
| 20403 | Slayer | 19,381 | 6 | 277 |
| 20404 | Sleepers (film) | 23,150 | 6 | 186 |
| 20405 | Slovakia national football team | 65,407 | 6 | 68 |
| 20406 | Slovenia national football team | 52,265 | 6 | 85 |
| 20407 | Sniper (film series) | 19,463 | 6 | 398 |
| 20408 | Soccer Aid | 66,060 | 6 | 52 |
| 20409 | Social Democratic Party of Germany | 71,652 | 6 | 48 |
| 20410 | SoftBank Group | 51,081 | 6 | 55 |
| 20411 | Sol Bamba | 251,045 | 6 | 5 |
| 20412 | Solar eclipse of 12 August 2026 | 113,300 | 6 | 29 |
| 20413 | Solar eclipse of April 20, 2023 | 131,994 | 6 | 18 |
| 20414 | Soleil Moon Frye | 51,303 | 6 | 69 |
| 20415 | Solheim Cup | 32,128 | 6 | 152 |
| 20416 | Sonam Wangchuk | 32,765 | 6 | 141 |
| 20417 | Song of the South | 31,432 | 6 | 171 |
| 20418 | Sonia | 142,954 | 6 | 28 |
| 20419 | Sophia Hammons | 18,375 | 6 | 246 |
| 20420 | Soulmate (2023 film) | 12,012 | 6 | 758 |
| 20421 | Soundarya Sharma | 24,257 | 6 | 176 |
| 20422 | South Carolina Gamecocks women's basketball | 46,948 | 6 | 91 |
| 20423 | Southampton | 20,443 | 6 | 324 |
| 20424 | Sparks | 116,950 | 6 | 39 |
| 20425 | Spencer Tracy | 21,774 | 6 | 223 |
| 20426 | Spider-Man (2018 video game) | 13,700 | 6 | 638 |
| 20427 | Spike Fearn | 22,410 | 6 | 213 |
| 20428 | Spike Jonze | 30,295 | 6 | 138 |
| 20429 | Spiro Agnew | 41,542 | 6 | 84 |
| 20430 | Sport climbing at the 2024 Summer Olympics | 61,774 | 6 | 74 |
| 20431 | Springfield, Ohio, cat-eating hoax | 15,265 | 6 | 457 |
| 20432 | Sriti Jha | 35,281 | 6 | 107 |
| 20433 | Stabbing of Salman Rushdie | 33,091 | 6 | 157 |
| 20434 | Stacy Keibler | 54,984 | 6 | 59 |
| 20435 | Stake (online casino) | 14,300 | 6 | 434 |
| 20436 | Stalag Luft III | 23,105 | 6 | 237 |
| 20437 | Standoff at Eagle Pass | 111,309 | 6 | 32 |
| 20438 | Star Wars: Visions | 32,870 | 6 | 123 |
| 20439 | Starmer ministry | 73,005 | 6 | 88 |
| 20440 | Starship flight test 7 | 53,844 | 6 | 79 |
| 20441 | Stateira (wife of Alexander the Great) | 22,224 | 6 | 338 |
| 20442 | Status of Jerusalem | 18,678 | 6 | 447 |
| 20443 | Steamboat Willie | 93,151 | 6 | 59 |
| 20444 | Stella Assange | 128,185 | 6 | 14 |
| 20445 | Stephan El Shaarawy | 72,325 | 6 | 52 |
| 20446 | Stephen Bear | 44,014 | 6 | 51 |
| 20447 | Stephen Belichick | 35,033 | 6 | 97 |
| 20448 | Stephen Stills | 92,993 | 6 | 30 |
| 20449 | Steve Clarke | 43,641 | 6 | 79 |
| 20450 | Steve Cohen (businessman) | 66,904 | 6 | 61 |