| 16401 | Sasha Banks | 53,250 | 8 | 68 |
| 16402 | Sasha Colby | 31,314 | 8 | 120 |
| 16403 | Saturday Night's Main Event XXXVIII | 35,445 | 8 | 162 |
| 16404 | Saw III | 14,232 | 8 | 607 |
| 16405 | Sawai Mansingh Stadium | 24,015 | 8 | 187 |
| 16406 | Say Nothing (book) | 15,925 | 8 | 517 |
| 16407 | Scar (The Lion King) | 31,732 | 8 | 134 |
| 16408 | Scipio Africanus | 35,073 | 8 | 175 |
| 16409 | Scott Caan | 45,611 | 8 | 77 |
| 16410 | Scott Frost | 36,239 | 8 | 189 |
| 16411 | Scott Ritter | 32,596 | 8 | 209 |
| 16412 | Sean Kingston | 30,222 | 8 | 121 |
| 16413 | Sean P. Stellato | 51,419 | 8 | 55 |
| 16414 | Second Punic War | 44,927 | 8 | 111 |
| 16415 | Sednaya Prison | 125,780 | 8 | 24 |
| 16416 | Sedona Prince | 72,196 | 8 | 31 |
| 16417 | Selah Marley | 15,311 | 8 | 558 |
| 16418 | September 11 | 45,682 | 8 | 93 |
| 16419 | September 2025 lunar eclipse | 240,557 | 8 | 7 |
| 16420 | Sergio Brown | 65,353 | 8 | 32 |
| 16421 | Sergio Reguilón | 103,495 | 8 | 22 |
| 16422 | Sermon on the 'Mount (South Park) | 28,533 | 8 | 169 |
| 16423 | Seth Curry | 29,330 | 8 | 130 |
| 16424 | Seth Green | 20,702 | 8 | 254 |
| 16425 | Shab-e-Barat | 109,595 | 8 | 21 |
| 16426 | Shadow the Hedgehog | 19,896 | 8 | 235 |
| 16427 | Shahmaran | 18,459 | 8 | 405 |
| 16428 | Shamar Joseph | 199,500 | 8 | 18 |
| 16429 | Shaquil Barrett | 36,178 | 8 | 113 |
| 16430 | Shardlake (TV series) | 36,912 | 8 | 91 |
| 16431 | Shareef O'Neal | 15,555 | 8 | 438 |
| 16432 | Shashi Kapoor | 25,687 | 8 | 219 |
| 16433 | Shaun White | 23,472 | 8 | 218 |
| 16434 | Shawn Hatosy | 23,141 | 8 | 190 |
| 16435 | Sheng Thao | 40,197 | 8 | 81 |
| 16436 | Shibu Soren | 129,716 | 8 | 13 |
| 16437 | Shifting Gears (TV series) | 29,086 | 8 | 195 |
| 16438 | Shoaib Malik | 584,358 | 8 | 4 |
| 16439 | Shooting of Chris Kaba | 81,638 | 8 | 22 |
| 16440 | Shoshone | 13,827 | 8 | 712 |
| 16441 | Shri Thanedar | 83,600 | 8 | 34 |
| 16442 | Shriya Saran | 37,691 | 8 | 113 |
| 16443 | Siddique (actor) | 22,940 | 8 | 213 |
| 16444 | Siege of Gaza City | 16,734 | 8 | 402 |
| 16445 | Silentó | 69,376 | 8 | 42 |
| 16446 | Silk (character) | 21,717 | 8 | 300 |
| 16447 | Silverstone Circuit | 28,112 | 8 | 184 |
| 16448 | Singapore Saloon | 21,071 | 8 | 280 |
| 16449 | Sinterklaas | 27,299 | 8 | 150 |
| 16450 | Sitaare Zameen Par (film) | 69,810 | 8 | 32 |