| 17201 | DMX | 104,490 | 7 | 23 |
| 17202 | Dominic Arun | 17,900 | 7 | 281 |
| 17203 | Dominic Raiola | 30,359 | 7 | 149 |
| 17204 | Dominic Roque | 21,047 | 7 | 271 |
| 17205 | Don Cheadle | 61,225 | 7 | 48 |
| 17206 | Donda 2 | 68,691 | 7 | 28 |
| 17207 | Donna Mills | 64,028 | 7 | 60 |
| 17208 | Dorian Finney-Smith | 27,624 | 7 | 234 |
| 17209 | Dorothy Gale | 18,728 | 7 | 394 |
| 17210 | Doug Collins (politician) | 53,942 | 7 | 72 |
| 17211 | Drew Allar | 50,777 | 7 | 75 |
| 17212 | Drew Brees | 52,662 | 7 | 54 |
| 17213 | Duffy (singer) | 55,088 | 7 | 95 |
| 17214 | Duncan Scott (swimmer) | 61,538 | 7 | 78 |
| 17215 | Dušan Tadić | 72,753 | 7 | 46 |
| 17216 | Eastern equine encephalitis | 22,849 | 7 | 173 |
| 17217 | Easton Stick | 59,304 | 7 | 44 |
| 17218 | Echidna | 25,299 | 7 | 193 |
| 17219 | Eddie Hall | 32,553 | 7 | 110 |
| 17220 | Edge of Tomorrow | 13,591 | 7 | 804 |
| 17221 | Edie Brickell | 31,664 | 7 | 132 |
| 17222 | Edita Piekha | 27,442 | 7 | 170 |
| 17223 | Edmonton | 22,809 | 7 | 226 |
| 17224 | Eduardo Verástegui | 12,684 | 7 | 698 |
| 17225 | Edward Coristine | 39,176 | 7 | 68 |
| 17226 | Edward Furlong | 43,459 | 7 | 67 |
| 17227 | Edward Guinness, 1st Earl of Iveagh | 127,547 | 7 | 19 |
| 17228 | Edward Guinness, 4th Earl of Iveagh | 20,638 | 7 | 287 |
| 17229 | Edward Packard (writer) | 14,773 | 7 | 432 |
| 17230 | Edward R. Murrow | 129,874 | 7 | 23 |
| 17231 | Edwin Schlossberg | 47,925 | 7 | 75 |
| 17232 | Egypt national football team | 50,316 | 7 | 100 |
| 17233 | El Niño | 23,041 | 7 | 228 |
| 17234 | El Palmar, Murcia | 68,769 | 7 | 64 |
| 17235 | Elgin Marbles | 94,447 | 7 | 25 |
| 17236 | Elkie Brooks | 101,004 | 7 | 25 |
| 17237 | Ella Langley | 43,341 | 7 | 94 |
| 17238 | Ella Rubin | 27,028 | 7 | 167 |
| 17239 | Emancipation Proclamation | 41,456 | 7 | 76 |
| 17240 | Emily Austin (journalist) | 16,616 | 7 | 331 |
| 17241 | Emily Fairn | 36,661 | 7 | 123 |
| 17242 | Emily Strayer | 84,497 | 7 | 36 |
| 17243 | Emma Chamberlain | 23,544 | 7 | 259 |
| 17244 | En Vogue | 57,013 | 7 | 54 |
| 17245 | Endeavor (company) | 91,238 | 7 | 30 |
| 17246 | Enhypen | 15,158 | 7 | 560 |
| 17247 | Enriched uranium | 29,058 | 7 | 193 |
| 17248 | Enrico Fermi Award | 27,711 | 7 | 252 |
| 17249 | Episcopal Church (United States) | 81,384 | 7 | 44 |
| 17250 | Epstein didn't kill himself | 97,073 | 7 | 31 |